CD300f (IREM-1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD300f (IREM-1), Human |
| Clone | REA1129 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD300f (IREM-1) Antibody, anti-human, APC-Vio® 770, REAfinity™. Clone REA1129 recognizes the human CD300f antigen, also known as immune receptor expressed by myeloid cell 1 (IREM-1), which is a type I transmembrane glycoprotein member of the CD300 family. It is expressed on myeloid cells and in peripheral blood on monocytes and granulocytes. CD300f binds the p85α regulatory subunit of phosphoinositide 3-kinase (PI3K) and can enhance phagocytosis of apoptotic cells. | Additional information: Clone REA1129 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM |
| Gene, Accession # | Gene ID: 146722 |
| Catalog # | 130-119-647 |
| Price | $158 |
| Order / More Info | CD300f (IREM-1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Alvarez-Errico, D. et al. (2004) IREM-1 is a novel inhibitory receptor expressed by myeloid cells. Eur. J. Immunol. 34 (12): 3690-3701. | Alvarez-Errico, D. et al. (2007) The IREM-1 (CD300f) inhibitory receptor associates with the p85α subunit of phosphoinositide 3-kinase. J Immunol 178: 808-816. | Choi, S. C. et al. (2011) Cutting edge: mouse CD300f (CMRF-35-like molecule-1) recognizes outer membrane-exposed phosphatidylserine and can promote phagocytosis. J Immunol 187 (7): 3483-3487. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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