ACTC1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityACTC1, Human
CloneREAL1174
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatphycoerythrin (PE) conjugate
Size200 µL
Concentrationn/a
ApplicationsMICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence
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DescriptionACTC1 Antibody, anti-human, PE, REAdye_lease™. Clone REAL1174 is an antibody fragment derived from the full ACTC1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1174 recognizes ACTC1, which is also known as cardiac muscle alpha actin or Alpha-cardiac actin. It is an important protein of the thin filament in cardiac sarcomeres, which play a crucial role in muscle contraction and support the pump function of the heart. It belongs to the actin family, highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in eukaryotic cells. Mutations in ACTC1 lead to dilated cardiomyopathy. ACTC1 is considered as a prognostic marker for glioma and for liver metastasis. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogenn/a
Other Namescardiac muscle alpha actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTC
Gene, Accession #n/a
Catalog #130-129-694
Price$510
Order / More InfoACTC1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesOlson, T. M. et al. (1998) Actin mutations in dilated cardiomyopathy, a heritable form of heart failure. Science 280 (5364): 750-752. | Ohtaki, S. et al. (2017) ACTC1 as an invasion and prognosis marker in glioma. J Neurosurg. 126 (2): 467-475. | Eun-Kyung, K. et al. (2019) Proteomic Analysis of Primary Colon Cancer and Synchronous Solitary Liver Metastasi. Cancer Genomics Proteomics 16 (6): 583-592. | Ingles, J. et al. (2019) Evaluating the Clinical Validity of Hypertrophic Cardiomyopathy Genes. Circ Genom Precis Med 12 (2): e002460..
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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