CD32, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD32, Human |
| Clone | 2E1 |
| Host Species | Mouse |
| Reactive Species | human, nonhuman primate, other |
| Isotype | IgG2aκ |
| Format | PE-Vio 770 conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD32 Antibody, anti-human, PE-Vio® 770. CD32, also known as FcγRII, is a 40 kDa low affinity receptor for the Fc fragment of aggregated IgG. Due to alternative splicing three different isoforms of CD32 are expressed on hematopoietic cells: FcRIIA, FcRIIB, and FcRIIC. The cytoplasmic domains of FcRIIA and FcRIIC contain an activatory ITAM motif whereas FcRIIB is an inhibitory receptor containing an ITIM motif. Different isoforms of CD32 are expressed on B cells, monocytes, dendritic cells, granulocytes, and platelets. The monoclonal antibody 2E1 recognizes all isoforms of CD32 without blocking the binding of immune complexes. |
| Immunogen | n/a |
| Other Names | FCGR2A, CD32A, CDw32, FCG2, FCGR21, FcGR, IGFR2, FCGR2B, CD32B, FcγRII |
| Gene, Accession # | Gene ID: 2212 |
| Catalog # | 130-097-506 |
| Price | $350 |
| Order / More Info | CD32, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Bave, U. et al. (2003) Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG. J Immunol 171 (6): 3296-3302. | Van Den Herik-Oudijk, I. E. et al. (1994) Functional analysis of human Fc gamma RII (CD32) isoforms expressed in B lymphocytes. J Immunol 152 (2): 574-585. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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