Edit |   |
Antigenic Specificity | CD326 (EpCAM), Mouse |
Clone | REA977 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | VioBlue conjugate |
Size | 150 µg in 1 mL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD326 (EpCAM) Antibody, anti-mouse, VioBlue®, REAfinity™. Clone REA977 recognizes the CD326 (EpCAM) antigen, which is a 40 kDa transmembrane glycoprotein involved in cell adhesion, cell proliferation, and tumor progression. It functions as a homotypic calcium-independent cell adhesion molecule. CD326 (EpCAM) is broadly expressed on epithelial cells including definitive endoderm cells, keratinocytes, immature thymocytes, langerhans cells, lymph node dendritic cells, thymic dendritic cells, splenic dendritic cells, and tumor cells including almost all carcinomas. Moreover, CD326 (EpCAM) is expressed on mouse embryonic stem cells and was described as a marker for the identification of successfully reprogrammed induced pluripotent stem cells (iPS). | Additional information: Clone REA977 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Ep-CAM, EGP, KSA, TROP1, Ly74, Tacsd1, Tacstd1, GP40, EGP40, MK-1 |
Gene, Accession # | Gene ID: 17075 |
Catalog # | 130-117-759 |
Price | $445 |
Order / More Info | CD326 (EpCAM), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Borkowski, T. A. et al. (1996) Expression of gp40, the murine homologue of human epithelial cell adhesion molecule (Ep-CAM), by murine dendritic cells. Eur. J. Immunol. 26 (1): 110-114. | Nelson, A. J. et al. (1996) The murine homolog of human Ep-CAM, a homotypic adhesion molecule, is expressed by thymocytes and thymic epithelial cells. Eur. J. Immunol. 26 (2): 401-408. | Chen, H. F. et al. (2011) Surface marker epithelial cell adhesion molecule and E-cadherin facilitate the identification and selection of induced pluripotent stem cells. Stem Cell Rev. 7 (3): 722-735. |