CD121b (IL-1R2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD121b (IL-1R2), Human |
| Clone | REA744 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Mass cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD121b (IL-1R2) Antibody, anti-human, Biotin, REAfinity™. Clone REA744 recognizes the human CD121b antigen, also known as interleukin-1 receptor type II (IL-1R2). CD121b is a 60 kDa cytokine receptor, which is a ligand for interleukin-1 (IL-1). There are two forms of the IL-1 receptors. The type I receptor is mainly involved in transmitting the inflammatory effects of IL-1 while type II receptor plays a role as a suppressor of IL-1 activity by competing for IL-1 binding. | Additional information: Clone REA744 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | IL-1R-2, IL-1R-II, IL-1RII, IL-1R-beta, IL-1Rb |
| Gene, Accession # | Gene ID: 7850 |
| Catalog # | 130-111-270 |
| Price | $264 |
| Order / More Info | CD121b (IL-1R2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | McMahan, C. J. et al. (1991) A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J. 10 (10): 2821-2832. | Kuno, K. et al. (1994) The IL-1 receptor signaling pathway. J. Leukoc. Biol. 56 (5): 542-547. | Liu, C. et al. (1996) Cloning and characterization of an alternatively processed human type II interleukin-1 receptor mRNA. J. Biol. Chem. 271 (34): 20965-20972. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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