CD147, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD147, Human |
| Clone | REA282 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD147 Antibody, anti-human, FITC, REAfinity™. Clone REA282 recognizes the human CD147 antigen, a single-pass type I membrane protein which is also known as basigin (BSG) or extracellular matrix metalloproteinase inducer (EMMPRIN). CD147 is expressed by many cell types, including epithelial cells, endothelial cells, leukocytes, and tumor cells. It is present in vascular endothelium in non-neoplastic regions of the brain and in tumor cells, but not in proliferating blood vessels in malignant gliomas. CD147 has been implicated in a variety of physiological and pathological activities. It is best known for its ability to function as extracellular matrix metalloproteinase inducer, but has also been shown to regulate lymphocyte responsiveness, monocarboxylate transporter expression, and spermatogenesis. | Additional information: Clone REA282 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | BSG, 5F7, EMMPRIN, M6, OK, TCSF, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor (TCSF) |
| Gene, Accession # | Gene ID: 682 |
| Catalog # | 130-124-268 |
| Price | $92 |
| Order / More Info | CD147, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kasinrerk, W. et al. (1992) Human leukocyte activation antigen M6, a member of the Ig superfamily, is the species homologue of rat OX-47, mouse basigin, and chicken HT7 molecule. J Immunol 149 (3): 847-854. | Biswas, C. et al. (1995) The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res. 55 (2): 434-439. | Yurchenko, V. et al. (2006) Dealing with the family: CD147 interactions with cyclophilins. Immunology 117 (3): 301-309. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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