CD300e (IREM-2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD300e (IREM-2), Human |
| Clone | UP-H2 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1κ |
| Format | PerCP-Vio 700 conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD300e (IREM-2) Antibody, anti-human, PerCP-Vio® 700. The monoclonal antibody UP-H2 reacts with human CD300e, also known as IREM-2, LMIR6, or CMRF35-A5. This 34 kDa activating receptor of the immunglobulin superfamily is expressed on mature myeloid dendritic cells and monocytes and is down-regulated on immature dendritic cells. CD300e interacts with DAP-12, which mediates acivating signals. It is reported that the alloreactive response of naive T cells is enhanced by IREM-2 activation of mDCs. |
| Immunogen | n/a |
| Other Names | CD300LE, CLM-2, CMRF35-A5, IREM-2, PIgR-2, LMIR6 |
| Gene, Accession # | n/a |
| Catalog # | 130-101-792 |
| Price | $151 |
| Order / More Info | CD300e (IREM-2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Aguilar, H. et al. (2004) Molecular characterization of a novel immune receptor restricted to the monocytic lineage. J Immunol 173: 6703-6711. | Brckalo, T. et al. (2010) Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells. Eur. J. Immunol. 40 (3): 722-732. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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