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Antigenic Specificity | IL-4, Human |
Clone | REA895 |
Host Species | Recombinant Human |
Reactive Species | human, nonhuman primate, other |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-4 Antibody, anti-human, APC, REAfinity™. Clone REA895 recognizes the human interleukin-4 (IL-4), which is predominantly secreted by activated CD4+ memory and effector T?2 cells, basophils, and mast cells. It induces and supports humoral immune responses for the neutralization of extracellular pathogens. The T?2 types of immune mechanisms can also be involved in immunological disorders such as IgE-mediated allergy. | Additional information: Clone REA895 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | BCGF-1, BCGF1, BSF-1, BSF1 |
Gene, Accession # | Gene ID: 3565 |
Catalog # | 130-114-885 |
Price | $142 |
Order / More Info | IL-4, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Yokota, T. et al. (1986) Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities. Proc. Natl. Acad. Sci. U.S.A. 83 (16): 5894-5898. | Abrams, J. S. et al. (1992) Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol. Rev. 127: 5-24. | Brown, M. A. et al. (1997) Functions of IL-4 and control of its expression. Crit. Rev. Immunol. 17 (1): 1-32. |