Human Cullin-4B Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Cullin-4B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage. Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication. Required for ubi |
| Immunogen | Immunogen: Recombinant human Cullin-4B protein (1-200aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8557 / sc-5323 / sc-10782 |
| Other Names | [CUL-4B; CUL4B], [CUL4B; CUL4B; SFM2; MRXSC; CUL-4B; MRXHF2; MRXS15; KIAA0695; CUL-4B] |
| Gene, Accession # | [CUL4B], Gene ID: 8450, NCBI: NP_001073341.1, UniProt: Q13620 |
| Catalog # | MBS1492201 |
| Price | $120, $160 |
| Order / More Info | Human Cullin-4B Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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