INS, 35-64 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-INS, 35-64 antibody, protein, ELISA kits.
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| Antigenic Specificity | INS, 35-64 |
| Clone | [396CT20.4.4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM |
| Format | ascites |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This INS antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from human INS. After removal of the precursor signal peptide, proinsulinis post-translationally cleaved into three peptides: the B chainand A chain peptides, which are covalently linked via two disulfidebonds to form insulin, and C-peptide. Binding of insulin to theinsulin receptor (INSR) stimulates glucose uptake. A multitude ofmutant alleles with phenotypic effects have been identified. Thereis a read-through gene, INS-IGF2, which overlaps with this gene atthe 5' region and with the IGF2 gene at the 3' region. Alternativesplicing results in multiple transcript variants. [provided byRefSe |
| Immunogen | n/a |
| Other Names | [Insulin; Insulin B chain; Insulin A chain; INS] |
| Gene, Accession # | [INS], Gene ID: 3630, NCBI: NP_000198.1, UniProt: P01308 |
| Catalog # | MBS9200500 |
| Price | $370 |
| Order / More Info | INS, 35-64 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Hinks, A., et al. Ann. Rheum. Dis. 69(12):2169-2172(2010) Breuer, T.G., et al. Eur. J. Endocrinol. 163(4):551-558(2010) Andersen, M.K., et al. Diabetes Care 33(9):2062-2064(2010) Ferron, M., et al. Cell 142(2):296-308(2010) Authier, F., et al. J. Biol. Chem. 277(11):9437-9446(2002) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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