Phospho-MEF2A (Ser408) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-MEF2A (Ser408) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-MEF2A (Ser408) antibody detects endogenous levels of MEF2A. Function: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with |
| Immunogen | Immunogen: A synthesized peptide derived from human MEF2A around the phosphorylation site of Ser408. Subcellular Location: MEF2A: Nucleus. MEF2C: Nucleus. Tissue Specificity: Isoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Ra |
| Other Names | [ADCAD1; MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A); MEF2; MEF2A; MEF2A_HUMAN; Myocyte enhancer factor 2A; Myocyte-specific enhancer factor 2A; RSRFC4; RSRFC9; Serum response factor like protein 1; Serum response factor-like protein 1] |
| Gene, Accession # | [MEF2A], Gene ID: 4205, NCBI: NP_001124399.1, UniProt: Q02078 |
| Catalog # | MBS9600691 |
| Price | $240, $280 |
| Order / More Info | Phospho-MEF2A (Ser408) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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