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Antigenic Specificity | NALP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NALP10 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1β, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1β processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation. |
Immunogen | Immunogen: NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10. Buffer: NALP10 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NALP10; NOD8; PAN5; PYNOD; NALP10; CLR11.1; NOD8; NACHT; LRR and PYD domains-containing protein 10; Nucleotide-binding oligomerization domain protein 8; NLR family, pyrin domain containing 10], [NLRP10; NLRP10; NOD8; PAN5; PYNOD; NALP10; CLR11.1; NALP10; NOD8; PYNOD] |
Gene, Accession # | [NLRP10], Gene ID: 338322, NCBI: NP_789791, UniProt: Q86W26 |
Catalog # | MBS151157 |
Price | $375 |
Order / More Info | NALP10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |