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Antigenic Specificity | Dematin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Dematin Polyclonal Antibody detects endogenous levels of Dematin protein. Dematin actin binding protein encoded by DMTN is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correla |
Immunogen | Immunogen: Synthesized peptide derived from human Dematin around the non-phosphorylation site of S403 |
Other Names | [Rabbit Dematin; EPB49; Dematin; Erythrocyte membrane protein band 4.9] |
Gene, Accession # | [DMT], Gene ID: 2039, NCBI: NP_001107607.1, UniProt: Q08495 |
Catalog # | MBS9701875 |
Price | $130, $220, $325 |
Order / More Info | Dematin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |