Phospho- STAT5 (pTyr 694) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho- STAT5 (pTyr 694)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse, bovine, dog
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot, Immunohistochemistry
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DescriptionThis antibody recognizes STAT5 (pY694) with a phosphorylated sites of Tyr694. It does not cross-react with non-phosphospecific peptide. STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. STAT5 is tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin. Serine phosphorylation is also required for maximal transcriptional activity. NCoA-1/SRC-1 acts as a co-activator for both the a- and b-isoforms of STAT5.
ImmunogenAntigen Preparation: A synthetic peptide surrounding to the epitope -DGYVK-- with phosphorylation sites at Tyr694 of STAT5 protein from human, mouse and rat origins.
Other Names[Rabbit Phospho-STAT5 (pY694); Signal transducer and activator of transcription 5 (STAT5)], [stat5a]
Gene, Accession #[STAT5 (pY694)], Gene ID: 399176, NCBI: NP_001083890.1
Catalog #MBS462116
Price$285
Order / More InfoPhospho- STAT5 (pTyr 694) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLin, J.X., et al. Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells. J. Biol Chem. 271: 10738, 2006
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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