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Antigenic Specificity | LRSAM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens (PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (PubMed:23245322, PubMed:25484098). |
Immunogen | Immunogen: Recombinant human E3 ubiquitin-protein ligase LRSAM1 protein (N-290AA) |
Other Names | [E3 ubiquitin-protein ligase LRSAM1Curated; Leucine-rich repeat and sterile alpha motif-containing protein 1; LRSAM1] |
Gene, Accession # | [LRSAM1], Gene ID: 90678, NCBI: NP_001005373.1, UniProt: Q6UWE0 |
Catalog # | MBS7045376 |
Price | $120, $160 |
Order / More Info | LRSAM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |