FOXO3/FOXO3A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFOXO3/FOXO3A
Clone[1B11]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, k
FormatProtein A purified
Size0.05 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: Human FOXO3. Transcriptional activator which triggers apoptosis in the absence ofsurvival factors, including neuronal cell death upon oxidative stress.Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.Participates in post-transcriptional regulation of MYC: followingphosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34cexpression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
ImmunogenImmunogen: FOXO3A (AAH21224, 361 a.a. ~ 460 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated
Other Names[Rabbit to Human FOXO3/FOXO3A; FOXO3; AF6q21; AF6q21 protein; Forkhead box O3; Forkhead box O3A; FOXO3A; FKHRL1P2; Forkhead box protein O3; FOXO2; FKHRL1]
Gene, Accession #[FOXO3/FOXO3A], Gene ID: 2309, NCBI: NP_001446.1, UniProt: O43524
Catalog #MBS2400891
Price$605
Order / More InfoFOXO3/FOXO3A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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