Edit |   |
---|---|
Antigenic Specificity | IL12B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pa |
Immunogen | Immunogen: Recombinant protein of human IL12B (NP 002178.2). |
Other Names | [interleukin-12 subunit beta; Interleukin-12 subunit beta; interleukin-12 subunit beta; interleukin 12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2] |
Gene, Accession # | [IL12B], Gene ID: 3593, NCBI: NP_002178.2, UniProt: P29460 |
Catalog # | MBS8567764 |
Price | $280 |
Order / More Info | IL12B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |