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Antigenic Specificity | PIAS4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PIAS4 Antibody: The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS4. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS4 interacts with p53 and blocks its ability to induce Bax and p21 transcription. PIAS4 is also important in the control of the ubiquitin-dependent proteasomal degradation of the Ets-1 transcription factor. PIAS4 has been implicated in the DNA-damage response pathway and is thought t |
Immunogen | Immunogen: PIAS4 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human PIAS4. Buffer: PIAS4 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PIAS4; PIASY; Piasg; ZMIZ6; PIASG; E3 SUMO-protein ligase PIAS4; PIASy; PIAS-gamma; protein inhibitor of activated STAT, 4], [PIAS4; PIAS4; PIASY; Piasg; ZMIZ6; PIAS-gamma; PIASG; PIAS-gamma] |
Gene, Accession # | [PIAS4], Gene ID: 51588, NCBI: NP_056981, UniProt: Q8N2W9 |
Catalog # | MBS151511 |
Price | $375 |
Order / More Info | PIAS4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |