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Antigenic Specificity | SMURF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes (PubMed: 23999003). |
Immunogen | Immunogen: Recombinant human E3 ubiquitin-protein ligase SMURF1 protein (198-374AA) |
Other Names | [E3 ubiquitin-protein ligase SMURF1; SMAD ubiquitination regulatory factor 1; SMAD-specific E3 ubiquitin-protein ligase 1; SMURF1; KIAA1625] |
Gene, Accession # | [SMURF1], Gene ID: 57154, NCBI: NP_001186776.1, UniProt: Q9HCE7 |
Catalog # | MBS7051296 |
Price | $160, $235 |
Order / More Info | SMURF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |