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Antigenic Specificity | PINCH |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PINCH antibody detects endogenous levels of total PINCH. Description: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading.Function: Adapter protein in a cytoplasmic complex linking beta-integrins to |
Immunogen | Immunogen: Purified recombinant fragment of human PINCH expressed in E. Coli Subcellular Location: Cell Junction > Focal Adhesion. Cell Membrane. Tissue Specificity: Expressed in most tissues except in the brain. |
Other Names | [2310016J22Rik; 4921524A02Rik; AI507642; AU021743; AW551584; C430041B13Rik; LIM and senescent cell antigen like domains 1; LIM and senescent cell antigen-like-containing domain protein 1; LIM zinc finger domain containing 1; LIM-type zinc finger domains 1; Lims1; LIMS1_HUMAN; Lims1l; Particularly interesting new Cys His protein 1; Particularly interesting new Cys His protein; Particularly interesting new Cys-His protein 1; PINCH 1; PINCH; PINCH-1; PINCH1; Renal carcinoma antigen NY REN 48; Renal carcinoma antigen NY-REN-48; senescent cell antigen; wu:fc32c03; zgc:112533] |
Gene, Accession # | [PINCH], Gene ID: 3987, NCBI: NP_001180411.1, UniProt: P48059 |
Catalog # | MBS9602337 |
Price | $235, $295, $370 |
Order / More Info | PINCH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |