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Antigenic Specificity | AQP0 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AQP0 antibody detects endogenous levels of total AQP0. Function: Water channel (PubMed:24120416). Channel activity is down-regulated by CALM when cytoplasmic Ca2+ levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity). Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (PubMed:24120416).Subunit Structure: Homotetramer (PubMed:24120416). Homooctamer formed by head-to-head interaction between homotetramers from adjoining membranes. Interacts with CALM; one CALM molecule interacts with the cytoplasmic domains of two aquaporins, leading to channel clo |
Immunogen | Immunogen: A synthesized peptide derived from human AQP0 Subcellular Location: Cell Membrane. Cell Junction > Gap Junction. Tissue Specificity: Major component of lens fiber gap junctions. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (91%), Bovine (91%), Horse (91%), Sheep (91%), Rabbit (91%), Dog (91%), Xenopus (91%) |
Other Names | [AQP 0; AQP0; Aquaporin; Aquaporin-0; Aquaporin0; Lens fiber major intrinsic protein; LIM 1; LIM1; Major intrinsic protein 26kD; Major intrinsic protein of lens fiber; MIP 26; mip; MIP_HUMAN; MIP26; MP 26; MP26; PALM] |
Gene, Accession # | [AQP0], Gene ID: 4284, NCBI: NP_036196.1, UniProt: P30301 |
Catalog # | MBS9601367 |
Price | $240, $280 |
Order / More Info | AQP0 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |