PVRL3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPVRL3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: PVRL3 antibody detects endogenous levels of total PVRL3. Function: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.Subunit Structure: Cis-and trans-homodimer. Can form trans-het
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (90%)
Other Names[CD113; CDw113; DKFZP566B0846; FLJ90624; Nectin-3; Nectin3; Poliovirus receptor related 3; Poliovirus receptor related protein 3; Poliovirus receptor-like 3; Poliovirus receptor-related protein 3; PPR3; PRR3; Pvrl3; PVRL3_HUMAN; PVRR3]
Gene, Accession #[PVRL3], Gene ID: 25945, NCBI: NP_001230215.1, UniProt: Q9NQS3
Catalog #MBS9605755
Price$240, $280
Order / More InfoPVRL3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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