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Antigenic Specificity | FAS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FAS Polyclonal Antibody detects endogenous levels of FAS protein. Tumor necrosis factor receptor superfamily member 6 encoded by FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. |
Immunogen | Immunogen: Synthesized peptide derived from human FAS around the non-phosphorylation site of Y291 |
Other Names | [Rabbit FAS; FAS; APT1; FAS1; TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD antigen CD95] |
Gene, Accession # | [FAS], Gene ID: 355, NCBI: NP_000034.1, UniProt: P25445 |
Catalog # | MBS9702033 |
Price | $130, $220, $325 |
Order / More Info | FAS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |