ATG4A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATG4A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionCysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 289-398 of human ATG4A (NP 443168.2).
Other Names[APG4A; AUTL2]
Gene, Accession #[ATG4A], Gene ID: 115201, NCBI: NP_443168.2, UniProt: Q8WYN0
Catalog #MBS8545019
Price$280
Order / More InfoATG4A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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