Phospho-Bcl-2 (Thr56) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Phospho-Bcl-2 (Thr56) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB); Immunohistochemistry (IHC); Immunoprecipitation (IP); Immunofluorescence (IF); ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Polyclonal antibody to detect Bcl-2 (Phospho-Thr56) in human samples. The Bcl-2 family of proteins is the best characterized protein family involved in the regulation of apoptotic cell death in variety of cells. Bcl2 is an integral outer mitochondrial membrane protein that regulates mitochondrial calcium homeostasis and proton flux. Several reports suggested that these phosphorylation sites may be targets of the ASK1/MKK7/JNK1 pathway and that phosphorylation of Bcl-2 may be a marker for mitotic events. Mutation of Bcl-2 at Thr56 or S87 inhibits its anti-apoptotic activity during glucocorticoid-induced apoptosis of T lymphocytes. |
| Immunogen | Immunogen: Synthesized peptide derived from human Bcl-2 around the phosphorylation site of Thr56 |
| Other Names | [BCL2; Apoptosis regulator Bcl-2], [BCL2; BCL2; Bcl-2; PPP1R50] |
| Gene, Accession # | [Bcl-2], Gene ID: 596, NCBI: NP_000624.2, UniProt: P10415 |
| Catalog # | MBS845890 |
| Price | $335 |
| Order / More Info | Phospho-Bcl-2 (Thr56) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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