FLI1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFLI1
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesreacts with: human, rat. predicted to work with: mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (Paraffin-embedded Section)
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DescriptionSpecificity: No cross reactivity with other proteins. Friend leukemia integration 1 transcription factor, also known as Transcription factor ERGB or Proto-oncogene Fli-1 is a protein that in humans is encoded by the human FLI1 gene. The fli1 protooncogene encodes a member of the ETS family of winged helix-turn-helix transcription factors. This gene is mapped to 11q24.3. Fli-1 is activated through retroviral insertional mutagenesis in 90% of F-MuLV-induced erythroleukemias. The constitutive activation of fli-1 in erythroblasts leads to a dramatic shift in the Epo/Epo-R signal transduction pathway, blocking erythroid differentiation, activating the Ras pathway, and resulting in massive Epo-independent proliferation of erythroblasts. These res
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human FLI1 (54-73aa QQEWINQPVRVNVKREYDHM), identical to the related rat and mouse sequences.
Other Names[Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; ERGB transcription factor; Ewing Sarcoma breakpoint region 2; EWSR 2; EWSR2; FLI 1; FLI 1 proto oncogene; FLI1; FLI1 EWS fusion gene; FLI1 proto oncogene; FLI1_HUMAN; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; SIC 1; SIC1; Transcription factor ERGB; Viral integration region FLI1], [FLI1; FLI1; EWSR2; SIC-1]
Gene, Accession #[FLI1], Gene ID: 2313, NCBI: Q01543.1, UniProt: Q01543
Catalog #MBS177100
Price$315
Order / More InfoFLI1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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