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Antigenic Specificity | FZD9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway. May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process (PubMed:27509850). During hippocampal development, regulates neuroblast proliferation and apoptotic cell death. Controls bon |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 469-591 of human FZD9 (NP 003499.1). |
Other Names | [FZD3; CD349] |
Gene, Accession # | [FZD9], Gene ID: 8326, NCBI: NP_003499.1, UniProt: O00144 |
Catalog # | MBS8547343 |
Price | $280 |
Order / More Info | FZD9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |