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Antigenic Specificity | CTPS2 (N-term), 77-105 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human CTPS2. CTPS2 catalyzes the formation of CTP from UTP with the concomitant eamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. |
Immunogen | n/a |
Other Names | [CTP synthase 2; CTP synthetase 2; UTP--ammonia ligase 2; CTPS2] |
Gene, Accession # | [CTPS2], Gene ID: 56474, NCBI: NP_001137474.1, UniProt: Q9NRF8 |
Catalog # | MBS9203789 |
Price | $165, $370 |
Order / More Info | CTPS2 (N-term), 77-105 Antibody from MYBIOSOURCE INC. |
Product Specific References | Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006) |