I-kappa-Ba (Tyr-42), phospho-specific Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-I-kappa-Ba (Tyr-42), phospho-specific antibody, protein, ELISA kits.
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| Antigenic Specificity | I-kappa-Ba (Tyr-42), phospho-specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was cross-adsorbed to phospho-tyrosine coupled to agarose then affinity purified using phospho- I-kappa-B-beta (Tyr-42) peptide (without carrier). The antibody detects a 38 kDa* protein on SDS-PAGE immunoblots of A431 and Jurkat cells treated with pervanadate, but not in control cells. Due to homologies to tyrosine sites on other proteins, it is recommended that the antibody be used to detect phosphorylation of immunoprecipitated I-kappa-B-alpha. The NF-kB/Rel transcription factors are present in the cytosol in an inactive state complexed with the inhibitory IkB proteins. Activation of IkBa occurs through both serine and tyrosine phosphorylation events. Activation through phosphorylation at Ser-32 and Ser-36 is followed by pro |
| Immunogen | Immunogen: IkBa (Tyr-42) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 42 of human IkBa. This peptide sequencehas low homology to other IkB proteins, but does have some homology to unrelated proteins that may have a conserved tyrosine phosphorylationmotif. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS472028 |
| Price | $385 |
| Order / More Info | I-kappa-Ba (Tyr-42), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Bui, N.T. et al. (2001) J Cell Biol 152(4):753. (Background)• Waris et al. (2003) J Biol Chem 278(42):40778. (Background)• Naidu, S. et al. (2008) J Immunol. 181:4113. (WB: Mouse RAW264.7)• Sethi, G. et al. (2007) Oncogene 26(52):7324. (WB: H. epithelial H1299, Y42F)• Boosani, C.S. et al. (2007) Blood 110(4):1168. (WB: M. lung endothelial, MLEC) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
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