Diablo Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Diablo |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The mitochondrial protein Smac/DIABLO (second mitochondria-derived activator) performs a critical function in apoptosis by eliminating the inhibitory effect of IAPs (inhibitor of apoptosis proteins) on caspases. The newly synthesized Smac protein contains 239 amino acids. Its N-terminal 55 residues encode the mitochondrial-targeting sequence and are proteolytically removed in the mature Smac protein. In the intrinsic cell death pathway, the key event leading to the activation of caspases is the release of several pro-apoptotic proteins such as Smac/DIABLO from the intermembrane space of mitochondria into the cytosol. During apoptosis, Smac is released from mitochondria and re-activates the processed initiator and effector caspases by reliev |
| Immunogen | Immunogen: Diablo antibody was raised in Rabbit using a synthetic target peptide as the immunogen |
| Other Names | [Rabbit Diablo; Diablo; Diablo; DIABLO; diablo; IAP-binding mitochondrial protein; BOS_16495; DBO; DFNA64; diablo homolog; diablo homolog (Drosophila); diablo homolog; mitochondrial; DIABLO-S; direct IAP binding protein with low PI; Direct IAP-binding protein with low pI; hCG_1782202; mitochondrial diablo; mitochondrial diablo-like protein; mitochondrial Smac protein; Second mitochondria-derived activator of caspase; second mitochondrial derived activator of caspases; Smac; smac3; XSmac] |
| Gene, Accession # | [DIABLO], Gene ID: 53556, NCBI: NP_001261892.1 |
| Catalog # | MBS5310050 |
| Price | $375 |
| Order / More Info | Diablo Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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