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Antigenic Specificity | Human p75NTR Extracellular |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The p75NTR receptor is a member of the TNF receptor superfamily. p75NTR, like all the superfamily members is a type I transmembrane protein with tandem cysteine-rich domains in the extracellular portion and a intracellular death domain. p75NTR binds its ligands as a homodimer but can also form heterodimers with other receptors such as TrkA, TrkB, TrkC, Nogo receptor and sortilin. The precise multimeric receptor complex formed between p75NTR and the other receptors will determine the ligand being recognized (see below) and the biological response to its binding. As it name implies, p75NTR binds all the neurotrophins (NGF, BDNF, NT-3 and NT-4) with similar nM affinities. Co-expression of p75NTR with the Trk receptors enhances the ability to b |
Immunogen | Immunogen: Peptide CEEIPGRWITRSTPPE corresponding to residues 188-203 of human p75NTR (SwissProt accession P08138). |
Other Names | Human p75NTR Extracellular (p75 Neurotrophin Receptor, Low Affinity NGF Receptor, TNFR Superfamily Member 16, CD271) |
Gene, Accession # | [p75NTR] |
Catalog # | MBS4157667 |
Price | $725 |
Order / More Info | Human p75NTR Extracellular Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |