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Antigenic Specificity | Uba2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Uba2 protein. The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.Mark H. L. Lambermon, Mol. Cell. Biol., Jun 2002; 22: 4346 - 4357. Kyoung-Seok Ryu, J. Biol. Chem., Sep 2003; 278: 36621 - 36627. R. Jrgen Dohmen, J. Biol. Chem., Jul 1995; 270: 18099. Yoshiaki Azuma, FASEB J, Jun 2001; 10.1096. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human Uba2. |
Other Names | [ANTHRACYCLINE-associated resistance ARX; ARX; EC 6.3.2.-; SUMO-1 activating enzyme subunit 2; UBA2] |
Gene, Accession # | [Uba2], Gene ID: 10054, NCBI: NP_005490.1, UniProt: Q9UBT2 |
Catalog # | MBS9405243 |
Price | $200, $255 |
Order / More Info | Uba2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |