CD86 (Dendritic Cells Maturation Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD86 (Dendritic Cells Maturation Marker)
Clone[BU63]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFunctional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin
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DescriptionRecognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the majo
ImmunogenImmunogen: ARH-77 (B-lymphoblastoid cell line)
Other Names[Activation B7-2 antigen; B lymphocyte activation antigen B72; CD28 antigen ligand 2; CD28LG2; CLS1; CTLA-4 counter-receptor B7.2; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly-58; MB7-2; TS/A-2], [CD86; CD86; B70; B7-2; B7.2; LAB72; CD28LG2; CD28LG2]
Gene, Accession #[CD86], Gene ID: 942, NCBI: NP_001193853.1, UniProt: P42081
Catalog #MBS438121
Price$190, $340, $340
Order / More InfoCD86 (Dendritic Cells Maturation Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesEngel P et. al. Blood. 1994;84(5):1402-7.Caux C et. al. J Exp Med. 1994;180(5):1841-7. Mauri D et. al. J Immunol. 1995;155(1):118-27.Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995).Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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