ASC Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ASC |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ASC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1. Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3, 4). Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues. |
| Immunogen | Immunogen: ASC antibody was raised against a 14 amino acid peptide near the carboxy terminus of human ASC. Buffer: ASC Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [ASC; ASC; TMS; TMS1; CARD5; TMS-1; ASC; Apoptosis-associated speck-like protein containing a CARD; Caspase recruitment domain-containing protein 5; hASC; PYD and CARD domain containing], [PYCARD; PYCARD; ASC; TMS; TMS1; CARD5; TMS-1; ASC; CARD5; TMS1; hASC] |
| Gene, Accession # | [PYCARD], Gene ID: 29108, NCBI: BAA87339, UniProt: Q9ULZ3 |
| Catalog # | MBS150936 |
| Price | $375 |
| Order / More Info | ASC Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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