TOR1A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TOR1A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TOR1A antibody detects endogenous levels of total TOR1A. Description: The neurological condition Dystonia is associated with sustained muscle contractions and abnormal posturing (1). TorsinA, torsinB, torp2A and torp3A belong to the family of ATPases associated with cellular activites (AAA+) and mutations in torsinA cause early onset dystonia (2). TorsinA has been shown to suppress intracellular protein aggregation in C. elegans and possesses chaperon activity. Interestingly, torsinA is highly expressed in dopaminergic neurons and associates with alpha-synuclein in Lewy bodies, which pathologically characterize Parkinson's Disease (3-5).Function: Protein with chaperone functions important for the control of protein folding, |
| Immunogen | Immunogen: A synthesized peptide derived from human TOR1A Subcellular Location: Endoplasmic Reticulum; Cytoskeleton; Nucleus Tissue Specificity: Widely expressed. Highest levels in kidney and liver. In the brain, high levels found in the dopaminergic neurons of the substantia nigra pars compacta, as well as in the neocortex, hippocampus and cerebellum. Also highly expressed in the spinal cord. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Bovine (100%), Horse |
| Other Names | [DQ2; Dystonia 1; Dystonia 1 protein; Dystonia 1 torsion; Dyt1; TOR1A; TOR1A_HUMAN; Torsin 1A; Torsin A; Torsin family 1 member A; Torsin family 1, member A (torsin A); Torsin-1A] |
| Gene, Accession # | [TOR1A], Gene ID: 1861, NCBI: NP_000104.1, UniProt: O14656 |
| Catalog # | MBS9607452 |
| Price | $240, $280 |
| Order / More Info | TOR1A Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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