ZRANB3 - C-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityZRANB3 - C-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, horse, human, porcine
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against ZRANB3. It was validated on Western BlotTarget Description: ZRANB3 is a DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. It is recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, it also catalyzes the fork regression
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ZRANB3
Other Names[DNA annealing helicase and endonuclease ZRANB3 isoform 2; DNA annealing helicase and endonuclease ZRANB3; DNA annealing helicase and endonuclease ZRANB3; zinc finger RANBP2-type containing 3; Annealing helicase 2; AH2; Zinc finger Ran-binding domain-containing protein 3Including the following 2 domains:DNA annealing helicase ZRANB3 (EC:3.6.4.-); Endonuclease ZRANB3 (EC:3.1.-.-)]
Gene, Accession #[ZRANB3], Gene ID: 84083, NCBI: NP_001273497.1, UniProt: Q5FWF4
Catalog #MBS3219314
Price$335
Order / More InfoZRANB3 - C-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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