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Antigenic Specificity | ZRANB3 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, horse, human, porcine |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against ZRANB3. It was validated on Western BlotTarget Description: ZRANB3 is a DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. It is recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, it also catalyzes the fork regression |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ZRANB3 |
Other Names | [DNA annealing helicase and endonuclease ZRANB3 isoform 2; DNA annealing helicase and endonuclease ZRANB3; DNA annealing helicase and endonuclease ZRANB3; zinc finger RANBP2-type containing 3; Annealing helicase 2; AH2; Zinc finger Ran-binding domain-containing protein 3Including the following 2 domains:DNA annealing helicase ZRANB3 (EC:3.6.4.-); Endonuclease ZRANB3 (EC:3.1.-.-)] |
Gene, Accession # | [ZRANB3], Gene ID: 84083, NCBI: NP_001273497.1, UniProt: Q5FWF4 |
Catalog # | MBS3219314 |
Price | $335 |
Order / More Info | ZRANB3 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |