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Antigenic Specificity | CD80 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for T-lymphocyte activation antigen CD80(CD80) detection. Tested with WB in Rat. Background: Cluster of Differentiation 80(also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28(for autoregulation and intercellular association) and CTLA-4(for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. Reeves et al.(1997) stated that |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat CD80 (227-245aa DAHVSQNFTWEKPPEDPPD), different from the related mouse sequence by two amino acids. |
Other Names | n/a |
Gene, Accession # | [CD80], NCBI: O55202, UniProt: O55202 |
Catalog # | MBS176205 |
Price | $280 |
Order / More Info | CD80 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |