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Antigenic Specificity | CD15/ Lewis X antigen/ alpha-(1,3)-fucosyltransferase 4 |
Clone | [BRA4F1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC-frozen), Immunohistochemistry (IHC-paraffin), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody BRA4F1 is directed against human CD15. The antibody does not cross react with the sialylated form of CD15 (CD15s). CD15 is a carbohydrate that is referred to as the Lewis X antigen, also known as alpha-(1,3)-fucosyltransferase 4, which is expressed on a variety of glycolipids and glycoproteins found on the cell surface of neutrophils, monocytes, eosinophils and non-hematopoietic tissues including embryonic tissues. CD15 is reported to function as an adhesion molecule and is involved in chemotaxis and phagocytosis. Expression of CD15 is also associated with a wide variety of tumour cells including some adenocarcinomas and certain types of myeloid and lymphoid leukaemias. Reed-Sternberg cells, found in cases of Hodgkins Lymphoma, |
Immunogen | Source Note: BRA4F1 is a mouse IgM monoclonal antibody derived from the fusion of SP2.0-Ag14 mouse myeloma cells with splenocytes from a BALB/c mouse immunized with K562 cells. |
Other Names | [alpha-(1,3)-fucosyltransferase 4; Alpha-(1,3)-fucosyltransferase 4; alpha-(1,3)-fucosyltransferase 4; alpha-(1,3)-fucosyltransferase 4; Lewis X; fucT-IV; fucosyltransferase IV; ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; galactoside 3-L-fucosyltransferase; stage-specific embryonic antigen 1; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific); ELAM-1 ligand fucosyltransferase; Fucosyltransferase 4; Fucosyltransferase IV; Fuc-TIV; FucT-IV; Galactoside 3-L-fucosyltransferase], [FUT4; FUT4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; ELFT; FCT3A; Fuc-TIV; FucT-IV] |
Gene, Accession # | [CD15], Gene ID: 2526, NCBI: NP_002024.1, UniProt: P22083 |
Catalog # | MBS570325 |
Price | $415 |
Order / More Info | CD15/ Lewis X antigen/ alpha-(1,3)-fucosyltransferase 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | Chorvath B, Sedlak J, Sulikova M, Pleskova I, Augustinova M, Duraj J. Monoclonal antibodies (series Bra-) of broad (non-lineage) or restricted (myelomonocytic) reactivities elicited with granulocytes or K 562 cells. Neoplasma. 1989;36(6):633-42.2. CD15 workshop In Leucocyte Typing IV. White Cell Differentiation Antigens - International workshop and conference. Knapp W, Doeken B, Gilks EP, Schmidt RE, Stein H, von dem Borne A.E.G.Kr. Eds. Vienna, Oxford University Press.1989. |