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Antigenic Specificity | RCC1 |
Clone | [332CT2.1.1] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RCC1 monoclonal antibody is generated from mouse immunized with RCC1 recombinant protein. Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly. |
Immunogen | n/a |
Other Names | [Regulator of chromosome condensation; Cell cycle regulatory protein; Chromosome condensation protein 1; RCC1; CHC1] |
Gene, Accession # | [RCC1], Gene ID: 1104, NCBI: NP_001041659.1, UniProt: P18754 |
Catalog # | MBS9230941 |
Price | $370 |
Order / More Info | RCC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Tooley, C.E., et al. Nature 466 (7310):1125-1128 (2010). England, J.R., et al. J. Mol. Biol. 398 (4):518-529 (2010). Wong, C.H., et al. Nat. Cell Biol. 11 (1):36-45 (2009). Ho, C.Y., et al. J. Cell. Biochem. 105 (3):835-846 (2008). Hao, Y., et al. J. Cell Biol. 182 (5):827-836 (2008). |