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Antigenic Specificity | Bcl-2 (Center Ser70), 49-76 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.32 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Bcl-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-76 amino acids from the Central region of human Bcl-2. Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
Immunogen | n/a |
Other Names | [Apoptosis regulator Bcl-2; BCL2] |
Gene, Accession # | [BCL2], Gene ID: 596, NCBI: NP_000624.2, UniProt: P10415 |
Catalog # | MBS9208484 |
Price | $165, $370 |
Order / More Info | Bcl-2 (Center Ser70), 49-76 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |