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Antigenic Specificity | Phospho-STAT6-T645 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using Phospho-STAT6-T645 antibody. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding T645 of human STAT6 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | n/a |
Gene, Accession # | [STAT6-T645] |
Catalog # | MBS4153189 |
Price | $510 |
Order / More Info | Phospho-STAT6-T645 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |