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Antigenic Specificity | MCM4 (Phospho Ser54) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-MCM4 (S54) Polyclonal Antibody detects endogenous levels of MCM4 protein only when phosphorylated at S54. The protein encoded by MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA heli |
Immunogen | Immunogen: Synthesized peptide derived from human MCM4 around the phosphorylation site of S54 |
Other Names | [Rabbit MCM4 (phospho Ser54); MCM4; CDC21; DNA replication licensing factor MCM4; CDC21 homolog; P1-CDC21] |
Gene, Accession # | [MCM4], Gene ID: 4173, NCBI: NP_005905.2, UniProt: P33991 |
Catalog # | MBS9705842 |
Price | $130, $220, $325 |
Order / More Info | MCM4 (Phospho Ser54) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |