Human 14-3-3 beta/alpha Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human 14-3-3 beta/alpha |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways (1,2). 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau, and eta that have been identified in mammals. The initially described alpha and delta isoforms are confirmed to be phosphorylated forms of beta and zeta, respectively (3). Through their amino-terminal alpha helical region, 14-3-3 proteins form homo- or heterodimers that interact with a wide variety of proteins: transcription factors, metabolic enzymes, cytoskeletal proteins, kinases, phosphatases, and other signaling molecules (3,4). The interaction of 14-3 |
| Immunogen | Immunogen: A fusion protein of human 14-3-3 beta/alpha |
| Other Names | [14-3-3 b/a; 14-3-3 b/a Rabbit pab; 14-3-3 beta/alpha Rabbit pab], [YWHAB; GW128; HS1; KCIP-1; 14-3-3;] |
| Gene, Accession # | Gene ID: 7529, NCBI: NP_003395.1, UniProt: P31946 |
| Catalog # | MBS125664 |
| Price | $275, $430 |
| Order / More Info | Human 14-3-3 beta/alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Muslin, A.J. and Xing, H. (2000) Cell Signal 12, 703-9.2. Mackintosh, C. (2004) Biochem. J. 381, 329-42.3. Dougherty, M.K. and Morrison, D.K. (2004) J. Cell Sci. 117, 1875-84.4. Yaffe, M.B. (2002) FEBS Lett. 513, 53-7.5. Bridges, D. and Moorhead, G.B. (2004) Sci. STKE 2004, re10. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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