DKK1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-DKK1 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | DKK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Dickkopf (DKK) family proteins consist of four members DKK1, DKK2, DKK3 and DKK4 that function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5 and LRP6 (1, 2). DKKs contain two cysteine-rich domains in which the positions of 10 cysteine residues are well conserved (3). Their expression is both temporally and spatially regulated during animal development (4). DKKs also bind with high affinity to transmembrane proteins Kremen1 and 2, which themselves also modulate Wnt signaling (5, 6). DKK1 was initially identified as an inducer of head formation in Xenopus embryos (7) and plays an important role in the regulation of bone mass (8-10). Increased levels of DKK1 are found in the majority of lung cancers, esophageal squamous cell c |
| Immunogen | Immunogen: Fusion protein of human DKK1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [DKK1; DKK-1; SK] |
| Gene, Accession # | [DKK1], Gene ID: 22943, NCBI: NP_036374.1, UniProt: O94907 |
| Catalog # | MBS8527337 |
| Price | $310 |
| Order / More Info | DKK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Mao, B. et al. (2001) Nature 411, 321-5. 2. Niehrs, C. (2006) Oncogene 25, 7469-81. 3. Krupnik, V.E. et al. (1999) Gene 238, 301-13. 4. Monaghan, A.P. et al. (1999) Mech Dev 87, 45-56. 5. Mao, B. et al. (2002) Nature 417, 664-7. 6. Davidson, G. et al. (2002) Development 129, 5587-96. 7. Glinka, A. et al. (1998) Nature 391, 357-62. 8. Baron, R. and Rawadi, G. (2007) Curr Osteoporos Rep 5, 73-80. 9. MacDonald, B.T. et al. (2007) Bone 41, 331-9. 10. Diarra, D. et al. (2007) Nat Med 13, 156-63. 11. Forget, M.A. et al. (2007) Br J Cancer 96, 646-53. 12. Yamabuki, T. et al. (2007) Cancer Res 67, 2517-25. 13. Kuphal, S. et al. (2006) Oncogene 25, 5027-36. 14. Aguilera, O. et al. (2006) Oncogene 25, 4116-21. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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