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Antigenic Specificity | gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) |
Clone | [SPM142] |
Host Species | Mouse |
Reactive Species | human. does not react with dog and rat. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. It stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignan |
Immunogen | Immunogen: Extract of pigmented melanoma metastases from lymph nodes |
Other Names | [95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog], [PMEL; PMEL; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E; D12S53E; PMEL17; SILV; ME20M; ME20-S; ME20S] |
Gene, Accession # | [SILV], Gene ID: 6490, NCBI: NP_001186982.1, UniProt: P40967 |
Catalog # | MBS438043 |
Price | $190, $340, $340 |
Order / More Info | gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Esclamado RM, et. al. American Journal of Surgery, 1986, 152(4):376-85. Gown AM, et. al. American Journal of Pathology, 1986, 123(2):195-203 |