PSMD10 (Center) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PSMD10 (Center) antibody, protein, ELISA kits.
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| Antigenic Specificity | PSMD10 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.48 |
| Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PSMD10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 43-76 amino acids from the Central region of human PSMD10. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pahway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis. |
| Immunogen | n/a |
| Other Names | [26S proteasome non-ATPase regulatory subunit 10; 26S proteasome regulatory subunit p28; Gankyrin; p28(GANK); PSMD10] |
| Gene, Accession # | [PSMD10], Gene ID: 5716, NCBI: NP_002805.1, UniProt: O75832 |
| Catalog # | MBS9209009 |
| Price | $165, $370 |
| Order / More Info | PSMD10 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Hori T.,et al.Gene 216:113-122(1998). Higashitsuji H.,et al.Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases. Wang H.,et al.Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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