GARS Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGARS
Clone[AT4E10]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1,k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionGARS, also known as glycyl-tRNA synthetase, is one of the aminoacyl-tRNA synthetase that charge tRNAs with their cognate amino acids. Defects in the gene encoding GlyRS is the cause of Charcot-Marie-Tooth disease type 2D (CMT2D), which is an autosomal dominant inherited disease characterized by severe weakness, atrophy and absence of deep tendon reflexes in the upper extremities. Defects in the GlyRS gene is also the cause of distal hereditary muscular neuropathy type V (HMN5), a disease similar to CMT2D, though the distal sensory involvement is less severe in HMN5 patients.
ImmunogenImmunogen: Recombinant human GARS (43-289aa) purified from E. coli
Other Names[Glycyl-tRNA synthetase; CMT2D; DSMAV; GlyRS; HMN5; SMAD1], [GARS; GARS; HMN5; CMT2D; DSMAV; GlyRS; SMAD1; AP-4-A synthetase; GlyRS]
Gene, Accession #[GARS], Gene ID: 2617, NCBI: NP_002038, UniProt: P41250
Catalog #MBS200317
Price$240, $315
Order / More InfoGARS Antibody from MYBIOSOURCE INC.
Product Specific ReferencesXie. W. (2007) Proc Natl Acad Sci U S A. 104: 9976-9981 ; Antonellis. A. (2003) AM J Hum Genet 72: 1293-1299
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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