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Antigenic Specificity | Phospho-AMPKalpha1 (Ser496) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); ELISA (EIA); Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of AMPKalpha1 protein when phosphorylated at Ser496 in human; mouse and rat. Catalytic subunit of AMP-activated protein kinase (AMPK); an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels; AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein; carbohydrate and lipid biosynthesis; as well as cell growth and proliferation. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2; RPTOR and ATG1/ULK1: in response to nutrient limitation; negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex an |
Immunogen | Immunogen: Synthesized peptide derived from human AMPKalpha1 around the phosphorylation site of S496 (420-500aa) |
Other Names | [PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1], [PRKAA1] |
Gene, Accession # | [AMPKalpha1], Gene ID: 5562, NCBI: NP_006242.5, UniProt: Q13131 |
Catalog # | MBS846125 |
Price | $335 |
Order / More Info | Phospho-AMPKalpha1 (Ser496) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |