Phospho-AMPKalpha1 (Ser496) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-AMPKalpha1 (Ser496)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB); ELISA (EIA); Immunohistochemistry (IHC)
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DescriptionPolyclonal antibody to detect endogenous levels of AMPKalpha1 protein when phosphorylated at Ser496 in human; mouse and rat. Catalytic subunit of AMP-activated protein kinase (AMPK); an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels; AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein; carbohydrate and lipid biosynthesis; as well as cell growth and proliferation. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2; RPTOR and ATG1/ULK1: in response to nutrient limitation; negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex an
ImmunogenImmunogen: Synthesized peptide derived from human AMPKalpha1 around the phosphorylation site of S496 (420-500aa)
Other Names[PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1], [PRKAA1]
Gene, Accession #[AMPKalpha1], Gene ID: 5562, NCBI: NP_006242.5, UniProt: Q13131
Catalog #MBS846125
Price$335
Order / More InfoPhospho-AMPKalpha1 (Ser496) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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