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Antigenic Specificity | IFNAR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for IFNAR2 detection. Tested with WB, IHC-P, IHC-F, ICC, FCM, Direct ELISA in Human.Background: Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene. It is mapped to 21q22.11. The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. |
Immunogen | Immunogen: E Coli-derived human IFNAR2 recombinant protein (Position: D33-Q466). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for IHC(P), IHC(F) and ICC. |
Other Names | [Interferon alpha/beta receptor 2; interferon alpha and beta receptor subunit 2; Interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha binding protein; IFN-alpha/beta receptor 2; Interferon alpha binding protein; Type I interferon receptor 2; IFNAR2; IFNABR; IFNARB] |
Gene, Accession # | [IFNAR2], Gene ID: 3455, NCBI: P48551.1, UniProt: P48551 |
Catalog # | MBS1752477 |
Price | $315 |
Order / More Info | IFNAR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Croze, E., Russell-Harde, D., Wagner, T. C., Pu, H., Pfeffer, L. M., Perez, H. D. The human type I interferon receptor: identification of the interferon beta-specific receptor-associated phosphoprotein. J. Biol. Chem. 271: 33165-33168, 1996. 2. Croze, E., Usacheva, A., Asarnow, D., Minshall, R.D., Perez, H.D., Colamonici, O. Receptor for activated C-kinase (RACK-1), a WD motif-containing protein, specifically associates with the human type I IFN receptor. J. Immun. 165: 5127-5132, 2000. |