Phospho-TFAP2C (Ser434) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-TFAP2C (Ser434)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mousepredicted: bovine, horse, sheep, rabbit, dog
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-TFAP2C(Ser434) Antibody detects endogenous levels of TFAP2C only when phosphorylated at Ser434. Description: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.Post Translational Modifications: Sumoylated on Lys-10; which inhibits transcri
ImmunogenImmunogen: A synthesized peptide derived from human TFAP2C around the phosphorylation site of Ser434. Tissue Specificity: During retinoic acid-mediated differentiation.
Other Names[Activating enhancer binding protein 2 gamma; Activating enhancer-binding protein 2 gamma; AP2-gamma; AP2C_HUMAN; AP2g; AP2gamma; ERF 1; ERF1; Estrogen receptor factor 1; hAP 2g; hAP2g; TFAP 2C; TFAP 2G; Tfap2c; TFAP2G; Transcription factor AP 2 gamma (activating enhancer binding protein 2 gamma); Transcription factor AP 2 gamma; Transcription factor AP-2 gamma; Transcription factor ERF 1; Transcription factor ERF-1; Transcription factor ERF1]
Gene, Accession #[TFAP2C], Gene ID: 7022, NCBI: NP_003213.1, UniProt: Q92754
Catalog #MBS9610444
Price$225, $280, $340
Order / More InfoPhospho-TFAP2C (Ser434) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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