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Antigenic Specificity | Phospho-TFAP2C (Ser434) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: bovine, horse, sheep, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-TFAP2C(Ser434) Antibody detects endogenous levels of TFAP2C only when phosphorylated at Ser434. Description: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.Post Translational Modifications: Sumoylated on Lys-10; which inhibits transcri |
Immunogen | Immunogen: A synthesized peptide derived from human TFAP2C around the phosphorylation site of Ser434. Tissue Specificity: During retinoic acid-mediated differentiation. |
Other Names | [Activating enhancer binding protein 2 gamma; Activating enhancer-binding protein 2 gamma; AP2-gamma; AP2C_HUMAN; AP2g; AP2gamma; ERF 1; ERF1; Estrogen receptor factor 1; hAP 2g; hAP2g; TFAP 2C; TFAP 2G; Tfap2c; TFAP2G; Transcription factor AP 2 gamma (activating enhancer binding protein 2 gamma); Transcription factor AP 2 gamma; Transcription factor AP-2 gamma; Transcription factor ERF 1; Transcription factor ERF-1; Transcription factor ERF1] |
Gene, Accession # | [TFAP2C], Gene ID: 7022, NCBI: NP_003213.1, UniProt: Q92754 |
Catalog # | MBS9610444 |
Price | $225, $280, $340 |
Order / More Info | Phospho-TFAP2C (Ser434) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |